Four friends are lost on a road trip, finding the house of a hidden cult that worships a being named Manos. They are led by the Master and his loyal servant, Torgo.
| Actor | Role |
|---|---|
 Jackey NeymanDebbie | Debbie |
 Tom NeymanThe Master | The Master |
 Diane MahreeMaggie | Maggie |
| BBryan JenningsSheriff Jennings | Sheriff Jennings |
| DDanielle DaggertyClara | Clara |
| SSteven ShieldsTorgo | Torgo |
| CChristina PezzoNicki | Nicki |
| NNuria AguilarPat | Pat |
| CChristopher BarnesJay | Jay |
| RRachel JacksonLenore | Lenore |
| BBryn KristiBride #2 | Bride #2 |
| TTonjia AtomicBride 3 | Bride 3 |
 George StoverMr. Pittock | Mr. Pittock |
| DDarlene DarwinDeputy Georgia | Deputy Georgia |
| DDerrick CareyVoice of Manos | Voice of Manos |