Manon escapes with the young nobleman Des Grieux, then becomes a high-class courtesan and finally forced to exile to America.
| Actor | Role |
|---|---|
 Alida ValliManon Lescaut | Manon Lescaut |
 Vittorio De SicaRenato Des Grieux | Renato Des Grieux |
 Lamberto PicassoIl visconte Des Grieux | Il visconte Des Grieux |
 Giulio DonadioIl marquese De Brienne | Il marquese De Brienne |
| DDino Di LucaIl sergente Lescaut | Il sergente Lescaut |
 Jole VoleriMusette | Musette |
| LLilia DaleDenise | Denise |
 Andrea ChecchiMarius | Marius |
 Guglielmo BarnabòGovernor of New Orleans | Governor of New Orleans |
| CCarlo BressanEdmond | Edmond |
 Aroldo TieriDe Brienne's Secretary | De Brienne's Secretary |
| OOreste Faresthe chaplain | the chaplain |
 Amina Pirani Magginoble gossiping | noble gossiping |
 Lola Braccinithe director | the director |
| PPina Gallinicreditor | creditor |
 Giuseppe Pierozzicreditor | creditor |
| CCesare Polaccocreditor | creditor |
| LLuigi AllodoliNot listed | Not listed |
 Diana KarenneNot listed | Not listed |
 Guido NotariNot listed | Not listed |
| MMichele RiccardiniNot listed | Not listed |