 Clark GableEdward J. 'Blackie' Gallagher | Edward J. 'Blackie' Gallagher |
 William PowellJim Wade | Jim Wade |
 Myrna LoyEleanor Packer | Eleanor Packer |
 Leo CarrilloFather Joe | Father Joe |
 Nat PendletonSpud | Spud |
 George SidneyPoppa Rosen | Poppa Rosen |
 Isabel JewellAnnabelle | Annabelle |
 Muriel EvansTootsie Malone | Tootsie Malone |
 Thomas E. JacksonAsst. Dist. Atty. Richard Snow | Asst. Dist. Atty. Richard Snow |
 Isabelle KeithMiss Adams | Miss Adams |
 Noel MadisonManny Arnold | Manny Arnold |
 Jimmy ButlerJim Wade as a Boy | Jim Wade as a Boy |
 Mickey RooneyBlackie as a Boy | Blackie as a Boy |
 Shirley RossSinger in Cotton Club | Singer in Cotton Club |
 Donald HainesYoung Spud (uncredited) | Young Spud (uncredited) |
 Frank ConroyBlackie's Defense Attorney (uncredited) | Blackie's Defense Attorney (uncredited) |
 Leonid KinskeyTrotskyite Slapping Poppa Rosen | Trotskyite Slapping Poppa Rosen |
 Oscar ApfelSpeaker of Assembly (uncredited) | Speaker of Assembly (uncredited) |
 William BaileyAl Barnes (uncredited) | Al Barnes (uncredited) |
 Curtis BentonAnnouncer (uncredited) | Announcer (uncredited) |
 John BleiferChauffeur (uncredited) | Chauffeur (uncredited) |
| JJames CurtisParty Leader (uncredited) | Party Leader (uncredited) |
 Vernon DentOtto (uncredited) | Otto (uncredited) |
| CCharles DunbarPanhandler (uncredited) | Panhandler (uncredited) |
 Jay EatonDrunk (uncredited) | Drunk (uncredited) |
| WWesley GiraudTough Boy (uncredited) | Tough Boy (uncredited) |
 John MarstonMr. Coates (uncredited) | Mr. Coates (uncredited) |
 Jack 'Tiny' LipsonUncle Angus (uncredited) | Uncle Angus (uncredited) |
| LLeo LanceLeon Trotsky (uncredited) | Leon Trotsky (uncredited) |
| PPat MoriarityTrotsky Heckler (uncredited) | Trotsky Heckler (uncredited) |
