Twelve men who belong to one of the world's most exclusive fraternities -- people who've walked on the surface of the moon -- are paid homage in this documentary. Using newsreel footage, rare NASA photographs, and digitally animated re-creations, Magnificent Desolation: Walking on the Moon examines the Apollo missions between 1969 and 1972 which put astronauts on the moon.
| Actor | Role |
|---|---|
 Tom HanksNarrator (voice) | Narrator (voice) |
 Bill PaxtonEd Mitchell (voice) | Ed Mitchell (voice) |
 Morgan FreemanNeil Armstrong (voice) | Neil Armstrong (voice) |
 Scott GlennCharles Duke (voice) | Charles Duke (voice) |
 Paul NewmanDave Scott (voice) | Dave Scott (voice) |
 John TravoltaJim Irwin | Jim Irwin |
 Matthew McConaugheyAl Bean (voice) | Al Bean (voice) |
 Matt DamonAl Shepard (voice) | Al Shepard (voice) |
 Bryan CranstonBuzz Aldrin (voice) | Buzz Aldrin (voice) |
 Rick GomezAlpha Station Commander (voice) | Alpha Station Commander (voice) |
 Colin HanksConspiracy Neil Armstrong | Conspiracy Neil Armstrong |
 Frank John HughesFuture Houston Capcom | Future Houston Capcom |
 Neal McDonoughReservoir Commander | Reservoir Commander |
 Barry PepperJohn Young | John Young |
 Kevin PollakDirector | Director |
| JJulie ShimerFuture Astronaut | Future Astronaut |
 Gary SiniseGene Cernan | Gene Cernan |
 Peter ScolariPete Conrad | Pete Conrad |
 Donnie WahlbergHelium 3 Commander | Helium 3 Commander |
 Rita WilsonBeta Station Commander | Beta Station Commander |