Set in Lisbon, Portugal, Madonna describes the World of Madame X in this documentary about her recent album. She is joined by collaborators that were part of or inspired Madame X.
| Actor | Role |
|---|---|
 MadonnaSelf | Self |
 Dino D'SantiagoSelf | Self |
 Mykki BlancoSelf | Self |
 MalumaSelf | Self |
 AnittaSelf | Self |
 Sofia BoutellaSelf | Self |
 Stella Mwale CicconeSelf | Self |
 Estere Mwale CicconeSelf | Self |