 Carole LombardJane Mason | Jane Mason |
 James StewartJohn Horace Mason | John Horace Mason |
 Charles CoburnJoseph Doolittle | Joseph Doolittle |
 Lucile WatsonHarriet Mason | Harriet Mason |
 Eddie QuillanConway | Conway |
 Alma KrugerSister Madeline | Sister Madeline |
 Irving BaconNewark Radio Operator (uncredited) | Newark Radio Operator (uncredited) |
 Raymond BaileySalt Lake City Hospital Chemist (uncredited) | Salt Lake City Hospital Chemist (uncredited) |
 Louise BeaversLily (uncredited) | Lily (uncredited) |
 Ward BondJim Hatton (uncredited) | Jim Hatton (uncredited) |
 Donald BriggsMr. Carter (uncredited) | Mr. Carter (uncredited) |
 Harlan BriggsJudge (uncredited) | Judge (uncredited) |
 Lane ChandlerRanger on Telephone (uncredited) | Ranger on Telephone (uncredited) |
| FFrederick ChapinYounger Doolittle (uncredited) | Younger Doolittle (uncredited) |
| RRuss ClarkOmaha Radio Operator (uncredited) | Omaha Radio Operator (uncredited) |
 Monte CollinsJuror (uncredited) | Juror (uncredited) |
| JJames ConatyCo-Worker (uncredited) | Co-Worker (uncredited) |
 Esther DaleAnnie (uncredited) | Annie (uncredited) |
 Harry DavenportDr. Healy (uncredited) | Dr. Healy (uncredited) |
 Edgar DearingMounted Policeman (uncredited) | Mounted Policeman (uncredited) |
 Harry DeppHutch (uncredited) | Hutch (uncredited) |
 Robert ElliottAirport Operations Manager (uncredited) | Airport Operations Manager (uncredited) |
 Fern EmmettFarmer's Wife (uncredited) | Farmer's Wife (uncredited) |
 Betty FarringtonHospital Cashier (uncredited) | Hospital Cashier (uncredited) |
| MMary FieldJohns Hopkins Technician (uncredited) | Johns Hopkins Technician (uncredited) |
 Ruth GilletteTipsy Blonde at New Year's Eve Party (uncredited) | Tipsy Blonde at New Year's Eve Party (uncredited) |
 Russell HoptonCollins (uncredited) | Collins (uncredited) |
 Olin HowlandFarmer (uncredited) | Farmer (uncredited) |
 Arthur HoytJury Foreman (uncredited) | Jury Foreman (uncredited) |
| VVictor Kilian Jr.Chicago Radio Operator (uncredited) | Chicago Radio Operator (uncredited) |
