 Peter LorreDoctor Gogol | Doctor Gogol |
 Frances DrakeYvonne Orlac | Yvonne Orlac |
 Colin CliveStephen Orlac | Stephen Orlac |
 Ted HealyReagan | Reagan |
 Isabel JewellMarianne (scenes deleted) | Marianne (scenes deleted) |
 Sara HadenMarie | Marie |
 Edward BrophyRollo | Rollo |
 Henry KolkerPrefect Rosset | Prefect Rosset |
 Keye LukeDr. Wong | Dr. Wong |
 May BeattyFrançoise | Françoise |
 Ian WolfeHenry Orlac, Stephen Orlac's Stepfather | Henry Orlac, Stephen Orlac's Stepfather |
| EEdward LippyPierre, Henry Orlac's Clerk (Uncredited) | Pierre, Henry Orlac's Clerk (Uncredited) |
 Frank DarienLavin, Waxwork Proprietor (Uncredited) | Lavin, Waxwork Proprietor (Uncredited) |
 Murray KinnellCharles, Theatre Official (Uncredited) | Charles, Theatre Official (Uncredited) |
 Rollo LloydVarsac, Fingerprint Expert (Uncredited) | Varsac, Fingerprint Expert (Uncredited) |
 Charles TrowbridgeDr. Marbeau | Dr. Marbeau |
 Nell CraigSuzanne (Uncredited) | Suzanne (Uncredited) |
 Robert Emmett KeaneRaoul (Uncredited) | Raoul (Uncredited) |
| AAgostino BorgatoStage Doorman (Uncredited) | Stage Doorman (Uncredited) |
 Billy GilbertAutograph Seeker on Train (Uncredited) | Autograph Seeker on Train (Uncredited) |
 Hooper AtchleyTrain Conductor (Uncredited) | Train Conductor (Uncredited) |
| MMaurice BrierreTaxi Driver (Uncredited) | Taxi Driver (Uncredited) |
 Julie CarterNurse (Uncredited) | Nurse (Uncredited) |
 Harvey ClarkStation Master (Uncredited) | Station Master (Uncredited) |
 Michael MarkExecution Official (Uncredited) | Execution Official (Uncredited) |
 Alphonse EthierAssistant Prefect (Uncredited) | Assistant Prefect (Uncredited) |
 Matty RoubertNewsboy (Uncredited) | Newsboy (Uncredited) |
 Otto HoffmanBlind Man (Uncredited) | Blind Man (Uncredited) |
 Cora Sue CollinsCrippled Girl (Uncredited) | Crippled Girl (Uncredited) |
 Sarah PaddenCrippled Girl's Mother (Uncredited) | Crippled Girl's Mother (Uncredited) |
