After getting dumped for the 11th time in a row, Frankie discovers that she has a "loser in love" gene, which predisposes her to chronic failure and rejection for the rest of her life. She decides to embark on a quest to change her romantic future.
| Actor | Role |
|---|---|
 Maeve DermodyFrankie | Frankie |
 Oliver FarnworthThomas | Thomas |
 Rory StroudWilbur | Wilbur |
 Elin PhillipsDebra | Debra |
 Ruth BrattJenny | Jenny |
 Emeka SesayKevin | Kevin |
| PPhilip Duguid-McQuillanAndy | Andy |
| TTim MarriottMalcolm | Malcolm |
| AAsif KhanDeepak | Deepak |
 John-Luke RobertsOliver | Oliver |
 Tovah FeldshuhDr. Elsa Blomgren | Dr. Elsa Blomgren |
 Tim BerringtonRestaurant Manager | Restaurant Manager |
 Dominic BoyleYoung Oliver | Young Oliver |
 Victoria EmslieSusannah | Susannah |
| KKiki KendrickCaroline the Venue Manager | Caroline the Venue Manager |