After being separated from her companions in a canyon plane crash, Lassie endures captivity, hops a freight train with runaway boys, battles a wolf, stops a stampede, saves a man, and overcomes injury—guided by a hawk—until she finally returns home.
| Actor | Role |
|---|---|
 Robert BrayCorey Stuart | Corey Stuart |
 Douglas HendersonDave Kirkland | Dave Kirkland |
| MMark TapscottDoctor | Doctor |
 LassieLassie the Dog | Lassie the Dog |
 Ricky KelmanSteve | Steve |
| CClyde HowdyHank Whitfield | Hank Whitfield |
 Roy RobertsMort Morgan | Mort Morgan |
| NNelson OlmstedDoc Hargus | Doc Hargus |