 James MasonProf. Humbert Humbert | Prof. Humbert Humbert |
 Shelley WintersCharlotte Haze | Charlotte Haze |
 Sue LyonDolores "Lolita" Haze | Dolores "Lolita" Haze |
 Gary CockrellRichard T. "Dick" Siller | Richard T. "Dick" Siller |
 Jerry StovinJohn Farlow | John Farlow |
 Diana DeckerJean Farlow | Jean Farlow |
 Lois MaxwellNurse Mary Lore | Nurse Mary Lore |
 Cec LinderPhysician | Physician |
| BBill GreeneGeorge Swine | George Swine |
 Shirley DouglasMrs. Starch | Mrs. Starch |
 Marianne StoneVivian Darkbloom | Vivian Darkbloom |
 Marion MathieMiss Lebone | Miss Lebone |
| JJames DyrenforthFrederick Beale Sr. | Frederick Beale Sr. |
| MMaxine HoldenMiss Fromkiss | Miss Fromkiss |
| JJohn HarrisonTom | Tom |
 Colin MaitlandCharlie Sedgewick | Charlie Sedgewick |
 Terry KilburnMan | Man |
| CC. Denier WarrenPotts | Potts |
 Roland BrandBill Crest | Bill Crest |
 Peter SellersClare Quilty | Clare Quilty |
 Irvin AllenHospital Attendant (uncredited) | Hospital Attendant (uncredited) |
| JJack ArmstrongGuest at High School Dance (uncredited) | Guest at High School Dance (uncredited) |
| BBeverly BennettFriend (uncredited) | Friend (uncredited) |
 Ed BishopAmbulance Attendant (uncredited) | Ambulance Attendant (uncredited) |
| AAngela BradleyFriend (uncredited) | Friend (uncredited) |
 Jim BradyPolice Convention Attendant (uncredited) | Police Convention Attendant (uncredited) |
| JJean CarntTeenager (uncredited) | Teenager (uncredited) |
| JJean CollinsTeenager (uncredited) | Teenager (uncredited) |
| FFred DavisGuest at High School Dance (uncredited) | Guest at High School Dance (uncredited) |
| JJennifer DoddDark-Haired Teenager (uncredited) | Dark-Haired Teenager (uncredited) |
