The passion that Joan of Castile, daughter of the Catholic Kings and heir to the throne, feels for her husband, Philip the Handsome, sovereign of the Netherlands and son of Maximilian of Austria and Mary of Burgundy, is not reciprocated. Her temperament, her jealousy and an unexpected tragedy will throw Joan into the dark realm of madness and obsession with death, the only realm where she will be a true queen…
| Actor | Role |
|---|---|
 Aurora BautistaDoña Juana de Castilla | Doña Juana de Castilla |
 Fernando ReyDon Felipe "el Hermoso" | Don Felipe "el Hermoso" |
 Sara MontielAldara | Aldara |
 Jorge MistralCapitán don Alvar | Capitán don Alvar |
 Jesús TordesillasDon Filiberto de Vere | Don Filiberto de Vere |
 Manuel LunaDon Juan Manuel | Don Juan Manuel |
 Juan EspantaleónAlmirante | Almirante |
 Ricardo AceroDon Carlos | Don Carlos |
 María CañeteDoña Elvira | Doña Elvira |
 Manuel ArbóMarlian | Marlian |
 Félix FernándezMesonero | Mesonero |
 Arturo MarínChieves | Chieves |
 Luis PeñaNoble | Noble |
 Conrado San MartínHernán | Hernán |
 Carmen de LucioAmante | Amante |
 Eduardo FajardoMarqués de Villena | Marqués de Villena |