Watson and Crick race to find the structure of DNA before Linus Pauling, Maurice Wilkins, or Rosalind Franklin can find the key to unlocking the secret.
| Actor | Role |
|---|---|
 Jeff GoldblumJim Watson | Jim Watson |
 Tim Pigott-SmithFrancis Crick | Francis Crick |
 Alan HowardMaurice Wilkins | Maurice Wilkins |
 Juliet StevensonRosalind Franklin | Rosalind Franklin |
| NNicholas FryRaymond Gosling | Raymond Gosling |
| RRachael WeaverFrench Girl | French Girl |
 Geoffrey ChaterSir Lawrence Bragg | Sir Lawrence Bragg |