The six-member crew of the International Space Station is tasked with studying a sample from Mars that may be the first proof of extra-terrestrial life, which proves more intelligent than ever expected.
| Actor | Role |
|---|---|
 Jake GyllenhaalDr. David Jordan | Dr. David Jordan |
 Ryan ReynoldsRory Adams | Rory Adams |
 Rebecca FergusonMiranda North | Miranda North |
 Hiroyuki SanadaSho Murakami | Sho Murakami |
 Olga DihovichnayaEkaterina Golovkina | Ekaterina Golovkina |
 Ariyon BakareHugh Derry | Hugh Derry |
 Naoko MoriKazumi | Kazumi |
 Haruka KurodaDoctor | Doctor |
| CCamiel Warren-TaylorDominique | Dominique |
 Alexandre Nguyen1st Fisherman | 1st Fisherman |
 Hiu Woong-Sin2nd Fisherman | 2nd Fisherman |
 David Muir20/20 Anchor | 20/20 Anchor |
 Allen McLeanStudent 1 | Student 1 |
 Jesus Del OrdenStudent 2 | Student 2 |
| LLeila GraceStudent 3 | Student 3 |
| MMari GvelesianiStudent 4 | Student 4 |
 Elizabeth Vargas20/20 Anchor | 20/20 Anchor |