Johnny Mack Brown follows his tried-and-true western formula in Law of the Panhandle. This time, U.S. Marshal Brown backs up Sheriff Tom Stocker (Riley Hill) in an ongoing battle against a marauding outlaw gang. The thieves, led by snarling Henry Faulkner (Myron Healey), hope to scare all the local ranchers off the land that will soon be purchased by the railroad that's coming through the territory.
| Actor | Role |
|---|---|
 Johnny Mack BrownU.S. Marshal Johnny Mack Brown | U.S. Marshal Johnny Mack Brown |
 Jane AdamsMargie Kendal | Margie Kendal |
 Riley HillSheriff Tom | Sheriff Tom |
 Marshall ReedEd Rance | Ed Rance |
 Myron HealeyHenry Faulkner | Henry Faulkner |
 Ted AdamsFred Kendal | Fred Kendal |
 Lee RobertsHenchman Judd | Henchman Judd |
 Carol HenryHenchman Ace | Henchman Ace |
 Milburn MoranteEzra Miller | Ezra Miller |
 Kermit MaynardLuke Winslow | Luke Winslow |
| BBob DuncanEvans | Evans |
 Tristram CoffinNarrator (uncredited) | Narrator (uncredited) |