It's 1876 and all the Indians are at peace except the Comanches lead by Black Cloud. When Black Cloud wipes out a town, only six soldiers are left and they head for the nearest fort. In the desert they are reinforced by members of a stagecoach and find some water at a deserted mission. Pinned down by Black Cloud they send an Indian boy who was Black Cloud's prisoner on to the fort while they try to bargain with Black Cloud whom they learn is without water.
| Actor | Role |
|---|---|
 Broderick CrawfordSgt. Matt Trainor | Sgt. Matt Trainor |
 Barbara HaleJulia Lanning | Julia Lanning |
 Johnny StewartLittle Knife | Little Knife |
 Lloyd BridgesJim Starbuck | Jim Starbuck |
 Mickey ShaughnessyRusty Potter | Rusty Potter |
 George MathewsRomany O'Rattigan | Romany O'Rattigan |
 Hugh SandersDenver Kinnaird | Denver Kinnaird |
| RRic RomanMartinez | Martinez |
 Chubby JohnsonHenry Ruppert | Henry Ruppert |
 Martin MilnerBilly Creel | Billy Creel |
 Milton ParsonsSatterlee the Prophet | Satterlee the Prophet |
| JJack WoodyCpl. Floyd | Cpl. Floyd |
 John War EagleBlack Cloud | Black Cloud |
 George ChesebroPete (uncredited) | Pete (uncredited) |
 Steve ForrestLt. Floyd (uncredited) | Lt. Floyd (uncredited) |
 Harry HarveyMunitions Man (uncredited) | Munitions Man (uncredited) |
 Jay SilverheelsIndian (uncredited) | Indian (uncredited) |
 Carleton YoungMaj. Lanning (uncredited) | Maj. Lanning (uncredited) |