 Steve CarellLarry 'Doc' Shepherd | Larry 'Doc' Shepherd |
 Bryan CranstonSal Nealon | Sal Nealon |
 Laurence FishburneReverend Richard Mueller | Reverend Richard Mueller |
 Yul VazquezLieutenant Colonel Wilits | Lieutenant Colonel Wilits |
 J. Quinton JohnsonCharlie Washington | Charlie Washington |
 Deanna Reed-FosterRuth Mueller | Ruth Mueller |
 Cicely TysonMrs. Hightower | Mrs. Hightower |
 Graham WolfeJohn Redman | John Redman |
 Jeff MonahanO'Toole | O'Toole |
 Richard RobichauxAnorak | Anorak |
 Dontez JamesDAFB Guard | DAFB Guard |
| TTammy TsaiMother (Irene) | Mother (Irene) |
 Richard BarlowAngry Father | Angry Father |
| CCathy O'DellGrieving Mother | Grieving Mother |
 Jane MowderRental Truck Employee | Rental Truck Employee |
| JJerry Lee TuckerRaincoat | Raincoat |
| MMarc MooreHyped-up Employee | Hyped-up Employee |
 Kate EastonPhone Shop Clerk | Phone Shop Clerk |
| SSarah SilkFront Desk Motel Employee | Front Desk Motel Employee |
| TTed Watts Jr.Leland | Leland |
| LLee HarringtonJamie | Jamie |
 Samuel DavisLarry Jr. (voice) | Larry Jr. (voice) |
| BBrian BowmanChurch Member (uncredited) | Church Member (uncredited) |
| KKelli CulbertsonBar Patron (uncredited) | Bar Patron (uncredited) |
 Chris DettoneTrain Passenger (uncredited) | Train Passenger (uncredited) |
| CChris DrexelBar Patron (uncredited) | Bar Patron (uncredited) |
| EEric FrankBar Patron Guy in Booth (uncredited) | Bar Patron Guy in Booth (uncredited) |
 John W. IwanonkiwJ Tinsley Amtrak Baggage Handler (uncredited) | J Tinsley Amtrak Baggage Handler (uncredited) |
| CChristopher NardizziTrain Passenger (uncredited) | Train Passenger (uncredited) |
 Phil NardozziBus Passenger (uncredited) | Bus Passenger (uncredited) |
