The film portrays the interaction of Johann Friedrich Struensee, a doctor treating the mentally ill Christian VII of Denmark, and his English consort Caroline Matilda.
| Actor | Role |
|---|---|
 O.W. FischerFriedrich Struensee | Friedrich Struensee |
 Odile VersoisQueen Mathilde | Queen Mathilde |
 Horst BuchholzKing Christian | King Christian |
 Fritz TillmannCount Rantzau | Count Rantzau |
 Elisabeth FlickenschildtQueen Juliane | Queen Juliane |
 Siegfried LowitzKammerherr Guldberg | Kammerherr Guldberg |
 Ingeborg SchönerGertrud von Eyben | Gertrud von Eyben |
 Helmuth LohnerKammerherr Graf Holck | Kammerherr Graf Holck |
| GGünther HadankNot listed | Not listed |
| WWilfried Jan HeynNot listed | Not listed |
| GGerhard RitterNot listed | Not listed |
| PPeter EsserNot listed | Not listed |
 Heini GöbelNot listed | Not listed |
 Georg LehnNot listed | Not listed |