The docudrama addresses the global threat posed by antibiotic-resistant bacteria. The film takes a scientifically grounded approach to exploring what lies ahead if antibiotics lose their effectiveness, and how and why resistance continues to spread. It places a particular focus on Germany—specifically the German healthcare system, German agriculture, and the German pharmaceutical industry.
| Actor | Role |
|---|---|
 Dietrich AdamDr. Ingo Johannsen | Dr. Ingo Johannsen |
 Stephan BaumeckerDr. Michael Kramer | Dr. Michael Kramer |
 Brigitte BöttrichInge Klausner | Inge Klausner |
| JJonas BroxtermannManfred Kowalski | Manfred Kowalski |
 Inga DietrichDr. Christine Albrecht | Dr. Christine Albrecht |
 Tim BeckmannNot listed | Not listed |
| AAlexander FriedrichNot listed | Not listed |
| CCan ImirzaliogluNot listed | Not listed |
 Julia KlöcknerNot listed | Not listed |
 Jerry KwartengDr. Jerome Weber | Dr. Jerome Weber |
| CChristoph LübbertNot listed | Not listed |
| GGerd-Ludwig MeyerNot listed | Not listed |
| GGergana MuskallaNot listed | Not listed |
 Paul AnthonyRobert Brockmann | Robert Brockmann |
| HHagen PfundnerNot listed | Not listed |
 Christiane RohdeNot listed | Not listed |
| KKornelia SmallNot listed | Not listed |
| LLothar H. WielerNot listed | Not listed |