 Daniel RadcliffeAllen Ginsberg | Allen Ginsberg |
 Dane DeHaanLucien Carr | Lucien Carr |
 Michael C. HallDavid Kammerer | David Kammerer |
 Jack HustonJack Kerouac | Jack Kerouac |
 Ben FosterWilliam Burroughs | William Burroughs |
 David CrossLouis Ginsberg | Louis Ginsberg |
 Jennifer Jason LeighNaomi Ginsberg | Naomi Ginsberg |
 Elizabeth OlsenEdie Parker | Edie Parker |
 John CullumProfessor Steeves | Professor Steeves |
 Brenda WehlePermissions Librarian | Permissions Librarian |
 Erin DarkeGwendolyn | Gwendolyn |
 Craig ChesterBusinessman | Businessman |
 Lenore HarrisDA Secretary | DA Secretary |
| MMark EthanCampus Guard | Campus Guard |
 Zach AppelmanLuke Detweiler | Luke Detweiler |
 David RascheDean | Dean |
| QQuinlan CorbettBilleting Officer | Billeting Officer |
| DDawn NewmanJazz Singer | Jazz Singer |
| CClancy O'ConnorTour Guide | Tour Guide |
 Jon DeVriesMr. Burroughs | Mr. Burroughs |
| LLeslie MeiselEdith Cohen | Edith Cohen |
 Sarah HollisHarlem Club Patron | Harlem Club Patron |
| NNicole SignorePage | Page |
| OOlen HolmSailor | Sailor |
 Michael CavadiasRay Conklin | Ray Conklin |
 Kyra SedgwickMarian Carr (uncredited) | Marian Carr (uncredited) |
| LLaura ObiolsKristina Laakson (uncredited) | Kristina Laakson (uncredited) |
| CColin Michael WalkerColumbia Classmate (uncredited) | Columbia Classmate (uncredited) |
| KKevyn SettleNorman (uncredited) | Norman (uncredited) |
 Martin Pfefferkorn1940s Prisoner (uncredited) | 1940s Prisoner (uncredited) |
