A lifelong bachelor confronts his intimacy issues when he sublets his apartment to a fetching biologist. His heartsick fish and his wise best buddy are on hand to provide perspective.
| Actor | Role |
|---|---|
 Matthew ModineMel | Mel |
 Gina GershonGinger | Ginger |
 Christy Scott CashmanDiana | Diana |
 Isiah Whitlock Jr.Freddie | Freddie |
 Fisher StevensBruce | Bruce |
 Kevin J. O'ConnorHarry | Harry |
 Lois ChilesJean | Jean |
 Stephen MailerBand Leader | Band Leader |
 Ewa Da CruzInga | Inga |
 Eddie Kaye ThomasSean | Sean |
 Ranjit ChowdhryDoorman | Doorman |
 Gloria ReubenMindy | Mindy |
| AAmy SaccoRita | Rita |
 Malachy McCourtRobert | Robert |
 Chuck PfeifferWalter | Walter |
| TTarajia MorrellSheila | Sheila |
 John Buffalo MailerLogan | Logan |
 Tamara WhatleyBeth | Beth |
 Samantha BuckMother | Mother |
| DDarrie LawrenceResident | Resident |
| AAlex WipfOld Man | Old Man |
 Ted SodBreakfast Man | Breakfast Man |
 Billy MerrittDriver | Driver |
| MManny SiverioSedan Driver | Sedan Driver |
| AAlisa ShamrowWedding Guest | Wedding Guest |
 Krista AyneSeductive Neighbor (uncredited) | Seductive Neighbor (uncredited) |
 Will BethencourtWedding Guest (uncredited) | Wedding Guest (uncredited) |
 Bill ChemerkaClub patron (uncredited) | Club patron (uncredited) |
| MMarc LazardBest Man (uncredited) | Best Man (uncredited) |