Two childhood friends — a New York hairstylist and a wanna-be musician — get mixed-up with the mob and are forced to deliver $50,000 to Australia, but things go all wrong when the money is lost to a wild kangaroo.
| Actor | Role |
|---|---|
 Jerry O'ConnellCharlie Carbone | Charlie Carbone |
 Anthony AndersonLouis Booker | Louis Booker |
 Estella WarrenJessie | Jessie |
 Christopher WalkenSalvatore 'Sal' Maggio | Salvatore 'Sal' Maggio |
 Michael ShannonFrankie Lombardo | Frankie Lombardo |
 Marton CsokasMr. Smith | Mr. Smith |
 Dyan CannonAnna Carbone | Anna Carbone |
 Frank WelkerKangaroo Jack (voice) | Kangaroo Jack (voice) |
 John McNeillCustoms Officer | Customs Officer |
 Bill HunterBlue | Blue |
 Tony NikolakopoulosSal's Capo | Sal's Capo |
 David NgoombujarraMr Jimmy | Mr Jimmy |
 Denise RobertsTansy | Tansy |
 Lara CoxCute Girl on Plane | Cute Girl on Plane |
 Damien FotiouBaby J | Baby J |
 Helen ThomsonTV Announcer | TV Announcer |
 Christopher James BakerCrumble | Crumble |
| AAntonio VitielloToot | Toot |
| MMarco SellittoBlasta | Blasta |
 Ryan GibsonHoon | Hoon |
 Adam GarciaKangaroo Jack/"Jackie Legs" (Uncredited0 | Kangaroo Jack/"Jackie Legs" (Uncredited0 |
| RRobert ReidYoung Charlie Carbone | Young Charlie Carbone |
| SShawn H. SmithYoung Louis Booker | Young Louis Booker |