Dolphy and Panchito reprise the roles they made popular in the 1960s, the wacky police detectives based on comic-strip characters.
| Actor | Role |
|---|---|
 DolphyKalabog | Kalabog |
| PPanchitoBosyo | Bosyo |
| RRolly QuizonTrese Medya | Trese Medya |
| JJoyce Ann BurtonMiss Kyuta | Miss Kyuta |
| BBong DimayacyacAnna | Anna |
 Zeny ZabalaOld Maid Rivah | Old Maid Rivah |
 Jaime FabregasDr. Kagaw | Dr. Kagaw |
| CConde UbaldoProf. Dokling | Prof. Dokling |
 ChuchiMerry Widow | Merry Widow |
| BBayani CasimiroNot listed | Not listed |
 Janno GibbsNot listed | Not listed |
| GGeorgie QuizonNot listed | Not listed |
 Soxy TopacioNot listed | Not listed |
| BBen JohnsonFrank Bok | Frank Bok |