 Benjamin BrattSuperman / Hernan Guerra (voice) | Superman / Hernan Guerra (voice) |
 Michael C. HallBatman / Kirk Langstrom (voice) | Batman / Kirk Langstrom (voice) |
 Tamara TaylorWonder Woman / Bekka (voice) | Wonder Woman / Bekka (voice) |
 Jason IsaacsLex Luthor (voice) | Lex Luthor (voice) |
 C. Thomas HowellDr. Will Magnus (voice) | Dr. Will Magnus (voice) |
 Paget BrewsterLois Lane (voice) | Lois Lane (voice) |
 Kari WahlgrenKaren Beecher / Livewire (voice) | Karen Beecher / Livewire (voice) |
 Grey DeLisleTina / Platinum (voice) | Tina / Platinum (voice) |
 Larry CedarPete Ross (voice) | Pete Ross (voice) |
 Eric BauzaRyan Choi / Stephen Shin (voice) | Ryan Choi / Stephen Shin (voice) |
 Penny Johnson JeraldPresident Waller (voice) | President Waller (voice) |
 Dee Bradley BakerRay Palmer / Tin (voice) | Ray Palmer / Tin (voice) |
 Richard ChamberlainHighfather (voice) | Highfather (voice) |
 Trevor DevallEmil Hamilton (voice) | Emil Hamilton (voice) |
 Dan GilvezanPat Dugan (voice) | Pat Dugan (voice) |
 Daniel HagenDr. Sivana (voice) | Dr. Sivana (voice) |
 Josh KeatonOrion (voice) | Orion (voice) |
 Arif S. KinchenMichael Holt / Bronze Tiger (voice) | Michael Holt / Bronze Tiger (voice) |
 Yuri LowenthalJor-El / Jimmy Olsen (voice) | Jor-El / Jimmy Olsen (voice) |
 Carl LumblySilas Stone (voice) | Silas Stone (voice) |
 Jim MeskimenVictor Fries (voice) | Victor Fries (voice) |
 Tayla ParxVictor Stone (voice) | Victor Stone (voice) |
 Khary PaytonJohn Henry Irons / Granny Goodness / Mugger (voice) | John Henry Irons / Granny Goodness / Mugger (voice) |
 Tahmoh PenikettSteve Trevor (voice) | Steve Trevor (voice) |
 Andrea RomanoJean Palmer (voice) | Jean Palmer (voice) |
 André SogliuzzoCop / Mr. Guerra (voice) | Cop / Mr. Guerra (voice) |
 Bruce ThomasGeneral Zod / Darkseid (voice) | General Zod / Darkseid (voice) |
 Lauren TomLara Lor-Van (voice) | Lara Lor-Van (voice) |
 Marcelo TubertTough Guy (voice) | Tough Guy (voice) |
 Bruce TimmBlockbuster (voice) (uncredited) | Blockbuster (voice) (uncredited) |
