In the tradition of V for Vendetta, Underworld and X Men, Johnny Virus takes place in the Chicago Underworld of futuristic 1940's.
| Actor | Role |
|---|---|
 Mark KielyJohnny VIrus | Johnny VIrus |
| PPatricia HellerFranziska | Franziska |
 Bob GolubBarny | Barny |
 Gregory Scott CumminsWalt | Walt |
 Richard V. LicataGiusseppi | Giusseppi |