With the price on his head ever increasing, John Wick uncovers a path to defeating The High Table. But before he can earn his freedom, Wick must face off against a new enemy with powerful alliances across the globe and forces that turn old friends into foes.
| Actor | Role |
|---|---|
 Keanu ReevesJohn Wick | John Wick |
 Donnie YenCaine | Caine |
 Bill SkarsgårdMarquis | Marquis |
 Ian McShaneWinston | Winston |
 Laurence FishburneBowery King | Bowery King |
 Lance ReddickCharon | Charon |
 Clancy BrownHarbinger | Harbinger |
 Hiroyuki SanadaShimazu | Shimazu |
 Rina SawayamaAkira | Akira |
 Scott AdkinsKilla | Killa |
 Aimée KwanMia | Mia |
 Marko ZarorChidi | Chidi |
 Natalia TenaKatia | Katia |
 Shamier AndersonTracker | Tracker |
 George GeorgiouThe Elder | The Elder |
 Yoshinori TashiroSumo #1 | Sumo #1 |
 Hishofuji HirokiSumo #2 | Sumo #2 |
| DDaiki SuzukiDaiki | Daiki |
 Julia Asuka RiedlOperator | Operator |
 Milena RendónOperator | Operator |
 Ivy QuainooOperator | Operator |
| IIrina TrifanovOperator | Operator |
 Iryna FedorovaBabushka | Babushka |
 Andrej KaminskyPriest | Priest |
 Sven MarquardtKlaus | Klaus |
 Raicho VasilevGerman Gangster | German Gangster |
 Lous and the YakuzaDJ | DJ |
 Christoph HofmannValet (uncredited) | Valet (uncredited) |
| VVhelma RichardsonGangster (uncredited) | Gangster (uncredited) |
 Jimmy MonetaParis Driver (uncredited) | Paris Driver (uncredited) |