 John F. KennedySelf (archive footage) | Self (archive footage) |
 Walter CronkiteSelf - Anchor, CBS News (voice) (archive sound) | Self - Anchor, CBS News (voice) (archive sound) |
 Peter JenningsSelf - ABC News Reporter | Self - ABC News Reporter |
 Cyril WechtSelf - MD, JD, President of Academy of Forensic Sciences | Self - MD, JD, President of Academy of Forensic Sciences |
| RRobert McClellandSelf - Medical Doctor | Self - Medical Doctor |
| MMarion JenkinsSelf - Medical Doctor | Self - Medical Doctor |
| RRichard DulanySelf - Medical Doctor | Self - Medical Doctor |
| CCharles J. CarricoSelf - Medical Doctor (archive footage) | Self - Medical Doctor (archive footage) |
 G. Robert BlakeySelf - Chief Counsel for the House Assassinations Committee | Self - Chief Counsel for the House Assassinations Committee |
| RRichard BissellSelf - CIA Director of Operations (archive footage) | Self - CIA Director of Operations (archive footage) |
| CCharles CabellSelf - General, CIA Deputy Director (archive footage) | Self - General, CIA Deputy Director (archive footage) |
 Richard M. Bissell Jr.Self - CIA Deputy Director for Plans (archive footage) | Self - CIA Deputy Director for Plans (archive footage) |
| RRamon RodriguezSelf - CIA Covert Operations (archive footage) | Self - CIA Covert Operations (archive footage) |
 Allen DullesSelf - CIA Director (archive footage) | Self - CIA Director (archive footage) |
 William ColbySelf - CIA Director (voice) (archive sound) | Self - CIA Director (voice) (archive sound) |
| GGuy BannisterSelf - FBI Chicago Chief (archive footage) | Self - FBI Chicago Chief (archive footage) |
 John ConnallySelf - Governor of Texas (archive footage) | Self - Governor of Texas (archive footage) |
| WWaggoner CarrSelf - Texas, Attorney General (archive footage) | Self - Texas, Attorney General (archive footage) |
| MMark WeissSelf - Acoustics Expert | Self - Acoustics Expert |
| AAubrey ReichSelf - Mortuary Technician (archive footage) | Self - Mortuary Technician (archive footage) |
| AAubrey RikeSelf - Ambulance Attendant, Parkland Hospital | Self - Ambulance Attendant, Parkland Hospital |
| AAndrey BillSelf - Parkland Hospital Nurse (archive footage) | Self - Parkland Hospital Nurse (archive footage) |
 George P. BushSelf - Co-director of Union Banking Co. (archive footage) | Self - Co-director of Union Banking Co. (archive footage) |
| EEric HamburgSelf - Author (archive footage) | Self - Author (archive footage) |
 Jack RubySelf - Former Associate of Richard Nixon (archive footage) | Self - Former Associate of Richard Nixon (archive footage) |
 George H. W. BushSelf (archive footage) | Self (archive footage) |
 Dwight D. EisenhowerSelf (archive footage) | Self (archive footage) |
| JJohn HankeyNarrator (voice) | Narrator (voice) |