 Charles LaughtonDr. Moreau | Dr. Moreau |
 Richard ArlenEdward Parker | Edward Parker |
 Leila HyamsRuth Thomas | Ruth Thomas |
 Bela LugosiThe Sayer of the Law | The Sayer of the Law |
 Kathleen BurkeLota the Panther Woman | Lota the Panther Woman |
 Arthur HohlMontgomery | Montgomery |
 Stanley FieldsCapt. Davies | Capt. Davies |
 Paul HurstCapt. Donahue | Capt. Donahue |
| HHans SteinkeOuran | Ouran |
 Tetsu KomaiM`ling | M`ling |
 George IrvingConsul | Consul |
| JJack BardetteUndetermined Role (uncredited) | Undetermined Role (uncredited) |
| EEvangelus BerbasUndetermined Role (uncredited) | Undetermined Role (uncredited) |
 Joe BonomoBeast (uncredited) | Beast (uncredited) |
 Buster BrodiePig Man - a Little Beast (uncredited) | Pig Man - a Little Beast (uncredited) |
| JJacob DanceBeast (uncredited) | Beast (uncredited) |
 Jimmy DimeSeaman (uncredited) | Seaman (uncredited) |
| HHarry EkezianGola (uncredited) | Gola (uncredited) |
 Charles GemoraGorilla on Pier (uncredited) | Gorilla on Pier (uncredited) |
 John GeorgeBeast (uncredited) | Beast (uncredited) |
| RRosemary GrimesSamoan Girl (uncredited) | Samoan Girl (uncredited) |
 Robert P. KerrUndetermined Role (uncredited) | Undetermined Role (uncredited) |
 Bob KortmanMr. Hogan (uncredited) | Mr. Hogan (uncredited) |
 Robert MilaschBeast (uncredited) | Beast (uncredited) |
 Constantine RomanoffBeast (uncredited) | Beast (uncredited) |
 SchlitzieFurry Manimal (uncredited) | Furry Manimal (uncredited) |
| JJack WaltersUndetermined Role (uncredited) | Undetermined Role (uncredited) |
 Duke YorkBeast (uncredited) | Beast (uncredited) |
