 Donald SutherlandMatthew Bennell | Matthew Bennell |
 Brooke AdamsElizabeth Driscoll | Elizabeth Driscoll |
 Leonard NimoyDr. David Kibner | Dr. David Kibner |
 Jeff GoldblumJack Bellicec | Jack Bellicec |
 Veronica CartwrightNancy Bellicec | Nancy Bellicec |
 Art HindleDr. Geoffrey Howell | Dr. Geoffrey Howell |
 Lelia GoldoniKatherine Hendley | Katherine Hendley |
 Kevin McCarthyRunning Man (Cameo) | Running Man (Cameo) |
 Don SiegelTaxi Driver | Taxi Driver |
 Tom LuddyTed Hendley | Ted Hendley |
 Stan RitchieStan | Stan |
| DDavid FisherMr. Gianni | Mr. Gianni |
| TTom DahlgrenDetective | Detective |
 Garry GoodrowDr. Boccardo | Dr. Boccardo |
| JJerry WalterRestaurant Owner | Restaurant Owner |
 Maurice ArgentChef | Chef |
| SSam ContiStreet Barker | Street Barker |
 Wood MoyMr. Tong | Mr. Tong |
| RR. WongMrs. Tong | Mrs. Tong |
| RRose KaufmanOutraged Woman | Outraged Woman |
 Joe BellanHarry | Harry |
| SSam HionaPoliceman #1 | Policeman #1 |
| LLee McVeighPoliceman #2 | Policeman #2 |
 Al NalbandianRodent Man | Rodent Man |
| LLee MinesSchool Teacher | School Teacher |
 Robert DuvallPriest on Swing (uncredited) | Priest on Swing (uncredited) |
 Michael ChapmanHealth Dept. Floor Cleaner (uncredited) | Health Dept. Floor Cleaner (uncredited) |
 Philip KaufmanCity Official on Phone (uncredited) (voice) | City Official on Phone (uncredited) (voice) |
| AAl PerezPG&E Man (uncredited) | PG&E Man (uncredited) |
| JJeff ScheftelPod Person at Party (uncredited) | Pod Person at Party (uncredited) |
