 Craig T. NelsonBob Parr / Mr. Incredible (voice) | Bob Parr / Mr. Incredible (voice) |
 Holly HunterHelen Parr / Elastigirl (voice) | Helen Parr / Elastigirl (voice) |
 Sarah VowellViolet Parr (voice) | Violet Parr (voice) |
 Huck MilnerDashiell 'Dash' Parr (voice) | Dashiell 'Dash' Parr (voice) |
 Catherine KeenerEvelyn Deavor (voice) | Evelyn Deavor (voice) |
 Eli FucileJack-Jack Parr (voice) | Jack-Jack Parr (voice) |
 Bob OdenkirkWinston Deavor (voice) | Winston Deavor (voice) |
 Samuel L. JacksonLucius Best / Frozone (voice) | Lucius Best / Frozone (voice) |
 Michael BirdTony Rydinger (voice) | Tony Rydinger (voice) |
 Sophia BushVoyd (voice) | Voyd (voice) |
 Brad BirdEdna 'E' Mode / Additional Voices (voice) | Edna 'E' Mode / Additional Voices (voice) |
 Phil LaMarrKrushauer / Helectrix / Additional Voices (voice) | Krushauer / Helectrix / Additional Voices (voice) |
 Isabella RosselliniAmbassador (voice) | Ambassador (voice) |
| AAdam GatesChad Brentley (voice) | Chad Brentley (voice) |
 Jonathan BanksRick Dicker (voice) | Rick Dicker (voice) |
 John RatzenbergerUnderminer (voice) | Underminer (voice) |
| BBill WiseScreenslaver / Pizza Guy (voice) | Screenslaver / Pizza Guy (voice) |
 Nicholas BirdMonster Jack-Jack Parr (voice) | Monster Jack-Jack Parr (voice) |
 Paul EidingReflux / Additional Voices (voice) | Reflux / Additional Voices (voice) |
 Barry BostwickMayor (voice) | Mayor (voice) |
| MMichael B. JohnsonVictor Cachet (voice) | Victor Cachet (voice) |
 Jere BurnsDetective (voice) | Detective (voice) |
 Adam RodriguezDetective (voice) | Detective (voice) |
 Kimberly Adair ClarkHoney (voice) | Honey (voice) |
| MMaeve AndrewsAdditional Voices (voice) | Additional Voices (voice) |
 Stephen ApostolinaAdditional Voices (voice) | Additional Voices (voice) |
 Robin Atkin DownesAdditional Voices (voice) | Additional Voices (voice) |
 Kimberly BaileyAdditional Voices (voice) | Additional Voices (voice) |
 Sola BamisAdditional Voices (voice) | Additional Voices (voice) |
 Steve BlumAdditional Voices (voice) | Additional Voices (voice) |
