The Pope is disturbed by the fact that today's youth are not as spiritually inclined as they should be, and so he decides to set up a Vatican television station and entice them back into the religion of their ancestors. In order to particularly grab the wandering flock, a priest invites the comedians from "The Other Sunday," an actual comedy program on Italian television, to perform on this new channel.
| Actor | Role |
|---|---|
 Roberto Benigniself | self |
| LLuciano De CrescenzoGod | God |
 Andy Luottoself | self |
 Isabella Rosselliniself | self |
 Diego AbatantuonoDon Gabriele | Don Gabriele |
| RRenzo Arboreself | self |
 Manfred FreybergerPapa Giovanni Paolo II | Papa Giovanni Paolo II |
 Mario Marencoself | self |
 Michael Pergolaniself | self |
 Salvatore BaccaroCorista | Corista |
 Mariangela Melatounselected actress | unselected actress |
 Graziano GiustiCardinal Richelieu | Cardinal Richelieu |
 Milly CarlucciAnnunciatrice Tv | Annunciatrice Tv |
 Ruggero Orlandoself | self |
 Silvia AnnichiaricoSegretaria di Renzo Arbore | Segretaria di Renzo Arbore |
| MMimma Nocellinun | nun |
 Neil HansenSorelle Bandiera | Sorelle Bandiera |
 Tito LeDucSorelle Bandiera | Sorelle Bandiera |
 Mauro BronchiSorelle Bandiera | Sorelle Bandiera |
| OOtto RichterOtto | Otto |
| BBernd WitthüserBarnelli | Barnelli |
| FFabrizio ZampaZampa | Zampa |
 Ferdinando MuroloMaestro coro spernacchiatori | Maestro coro spernacchiatori |
| MMatteo SalvatoreGallo | Gallo |
| GGerardo Gargiulospeaker | speaker |
 Martin ScorseseDirettore Tv | Direttore Tv |