 Oscar IsaacNick / Dante | Nick / Dante |
 Gal GadotGiulietta / Gemma | Giulietta / Gemma |
 Gerard ButlerLouie / Pope Bonifacio | Louie / Pope Bonifacio |
 John MalkovichJoe Black | Joe Black |
 Louis CancelmiLefty / Guido Novello Da Polenta | Lefty / Guido Novello Da Polenta |
 Sabrina ImpacciatoreDr. Susanna Pulice | Dr. Susanna Pulice |
 Franco NeroDon Lecco (86) | Don Lecco (86) |
 Benjamin ClementineMephistopheles | Mephistopheles |
 Paolo BonacelliPriest Of Alcamo | Priest Of Alcamo |
 Martin ScorseseIsaiah | Isaiah |
 Al PacinoUncle Carmine | Uncle Carmine |
 Jason MomoaRosario | Rosario |
 Ibrahim ElouahabiYoung Nick (8) | Young Nick (8) |
| GGavin WeingartenBoy With Wagon (11) | Boy With Wagon (11) |
 Dario SamacYoung Dante (14) | Young Dante (14) |
 Duke NicholsonBar Manager | Bar Manager |
 Denise CapezzaNick's Ex Girlfriend | Nick's Ex Girlfriend |
 Galen HopperNick's Daughter | Nick's Daughter |
 Lorenzo ZurzoloDon Lecco (30) | Don Lecco (30) |
 Vincenzo LetoDon Lecco's Father | Don Lecco's Father |
 Giorgia ArenaMistress (Don Lecco's Father) | Mistress (Don Lecco's Father) |
| AAlessandro De SimoneYoung Priest of Alcamo | Young Priest of Alcamo |
 Gustavo La VolpeMan From Palermo #1 | Man From Palermo #1 |
| GGiuseppe CutrullàMan From Palermo #2 | Man From Palermo #2 |
 Vincenzo ScuruchiMan From Palermo #3 | Man From Palermo #3 |
 Salvatore La MantiaElderly Guard (Don Lecco) | Elderly Guard (Don Lecco) |
 Dora RomanoOld Woman (Don Lecco) | Old Woman (Don Lecco) |
| FFabrizio FalangaGarage Attendant | Garage Attendant |
| AAlfonso VenersoSedan's Driver | Sedan's Driver |
 Guido CaprinoGuido Cavalcanti | Guido Cavalcanti |
