Secret agent Napoleon Solo fights to stop a top-secret plot to conquer the world.
| Actor | Role |
|---|---|
 Robert VaughnNapoleon Solo | Napoleon Solo |
 David McCallumIllya Kuryakin | Illya Kuryakin |
 Barry SullivanDr. Robert Kingsley | Dr. Robert Kingsley |
 Eleanor ParkerMargitta Kingsley | Margitta Kingsley |
 Leslie NielsenGeneral Maximilian Harmon | General Maximilian Harmon |
 Leo G. CarrollAlexander Waverly | Alexander Waverly |
 Tony BillSteven Garrow | Steven Garrow |
 Peter Mark RichmanMr. Webb | Mr. Webb |
 Albert PaulsenDr. Kurt Erikson | Dr. Kurt Erikson |
 Inger StrattonAnna Erikson | Anna Erikson |
 Hugh MarloweGrant | Grant |
| AAmy ThomsonMiss Carla | Miss Carla |
 Dan O'HerlihyProf. David Garrow | Prof. David Garrow |
 Ruth WarrickAlice Garrow | Alice Garrow |
 David HurstDr. Jan Vanovech | Dr. Jan Vanovech |
 Barbara MooreLisa Rogers | Lisa Rogers |
| AArthur HansonPaul Mackie | Paul Mackie |
 Richard BullCapt. Gelser | Capt. Gelser |
 Edgar StehliVeeth | Veeth |
| AAnnella BassettDr. Naomi Fisher | Dr. Naomi Fisher |
 Logan RamseyShip's Captain | Ship's Captain |
| GGuy LeeCab Driver | Cab Driver |
| RRay WeaverReporter | Reporter |
| MMichael MastersReporter | Reporter |