 Andy SambergJohnny (voice) | Johnny (voice) |
 Selena GomezMavis (voice) | Mavis (voice) |
 Kathryn HahnEricka (voice) | Ericka (voice) |
 Jim GaffiganVan Helsing (voice) | Van Helsing (voice) |
 Steve BuscemiWayne (voice) | Wayne (voice) |
 Molly ShannonWanda (voice) | Wanda (voice) |
 David SpadeGriffin (voice) | Griffin (voice) |
 Keegan-Michael KeyMurray (voice) | Murray (voice) |
 Brian HullDracula (voice) | Dracula (voice) |
 Fran DrescherEunice (voice) | Eunice (voice) |
 Brad AbrellFrankenstein (voice) | Frankenstein (voice) |
 Asher BlinkoffDennis (voice) | Dennis (voice) |
 Tyler BlevinsParty Monster (voice) | Party Monster (voice) |
| ZZoe BerriWinnie (voice) | Winnie (voice) |
 Genndy TartakovskyBlobby (voice) | Blobby (voice) |
 Asher BishopWesley (voice) | Wesley (voice) |
 Jennifer KluskaWendy (voice) | Wendy (voice) |
| VVictoria GomezYoung Mavis / Wilma (voice) | Young Mavis / Wilma (voice) |
 Derek DrymonHuman Zombie (voice) | Human Zombie (voice) |
 Aaron LaPlanteGremlin Pilot / Gremlin Stewardess (voice) | Gremlin Pilot / Gremlin Stewardess (voice) |
 Melissa SturmAirbag Monster / Phone Voice (voice) | Airbag Monster / Phone Voice (voice) |
 Chloé MalaiséFemale Newscaster (voice) | Female Newscaster (voice) |
 Scott UnderwoodMale Newscaster (voice) | Male Newscaster (voice) |
 Michelle MurdoccaWitch (voice) | Witch (voice) |
 William TownsendZombie (voice) | Zombie (voice) |
| DDavid BerónAdditional Voices (voice) | Additional Voices (voice) |
 Natalia CastellanosAdditional Voices (voice) | Additional Voices (voice) |
 Todd HaberkornAdditional Voices (voice) | Additional Voices (voice) |
 Jess HarnellAdditional Voices (voice) | Additional Voices (voice) |
 Marabina JaimesAdditional Voices (voice) | Additional Voices (voice) |
