 Piper CurdaMabel (voice) | Mabel (voice) |
 Bobby MoynihanKing George (voice) | King George (voice) |
 Jon HammMayor Jerry Generazzo (voice) | Mayor Jerry Generazzo (voice) |
 Kathy NajimyDr. Sam (voice) | Dr. Sam (voice) |
 Dave FrancoInsect King (voice) | Insect King (voice) |
 Eduardo FrancoLoaf (voice) | Loaf (voice) |
 Aparna NancherlaNisha (voice) | Nisha (voice) |
| TTom LawTom Lizard (voice) | Tom Lizard (voice) |
 Sam RichardsonConner (voice) | Conner (voice) |
 Melissa VillaseñorEllen (voice) | Ellen (voice) |
 Isiah Whitlock Jr.Bird King (voice) | Bird King (voice) |
 Steve PurcellAmphibian King (voice) | Amphibian King (voice) |
 Ego NwodimFish Queen (voice) | Fish Queen (voice) |
 Nichole SakuraReptile Queens (voice) | Reptile Queens (voice) |
 Meryl StreepInsect Queen (voice) | Insect Queen (voice) |
 Karen HuieGrandma Tanaka (voice) | Grandma Tanaka (voice) |
 Lila LiuYoung Mabel (voice) | Young Mabel (voice) |
 Eman Abdul-RazzakInsect Prince (voice) | Insect Prince (voice) |
 Vanessa BayerDiane (voice) | Diane (voice) |
 Joe SpanoAncient Beavertonian (voice) | Ancient Beavertonian (voice) |
 Matthew Yang KingAdditional Voices (voice) | Additional Voices (voice) |
 Bob PetersonAdditional Voices (voice) | Additional Voices (voice) |
 Lori AlanAdditional Voices (voice) | Additional Voices (voice) |
 Grey DeLisleAdditional Voices (voice) | Additional Voices (voice) |
 Laraine NewmanAdditional Voices (voice) | Additional Voices (voice) |
 Carlos AlazraquiAdditional Voices (voice) | Additional Voices (voice) |
 Rick ZieffAdditional Voices (voice) | Additional Voices (voice) |
 Alex DésertAdditional Voice (voice) | Additional Voice (voice) |
 Jeff PidgeonAdditional Voices (voice) | Additional Voices (voice) |
 Bill BarrettaAdditional Voices (voice) | Additional Voices (voice) |
