 Meryl StreepKay | Kay |
 Tommy Lee JonesArnold Soames | Arnold Soames |
 Steve CarellDr. Bernie Feld | Dr. Bernie Feld |
 Jean SmartEileen, Kay's Friend | Eileen, Kay's Friend |
 Marin IrelandMolly, Their Daughter | Molly, Their Daughter |
 Ben RappaportBrad, Their Son | Brad, Their Son |
 Brett RiceVince, Arnold's Friend | Vince, Arnold's Friend |
 Becky Ann BakerCora, The Waitress | Cora, The Waitress |
 Elisabeth ShueKaren, The Bartender | Karen, The Bartender |
 Charles TechmanCharlie, The Docent | Charlie, The Docent |
 Danny FlahertyDanny, The Bookstore Clerk | Danny, The Bookstore Clerk |
 Damian YoungMike, The Innkeeper | Mike, The Innkeeper |
 Mimi RogersCarol, The Neighbor | Carol, The Neighbor |
 Ann HaradaAnn | Ann |
 Jack HaleyJack, The Happy Husband | Jack, The Happy Husband |
 Patch DarraghMark, Their Son-in-Law | Mark, Their Son-in-Law |
 Susan MisnerDana, Doctor Feld's Wife | Dana, Doctor Feld's Wife |
 Rony ClantonRonnie, The Taxi Driver | Ronnie, The Taxi Driver |
| JJohn SrednickiJohn, The Waiter | John, The Waiter |
 Madeline RuskinMaddie, Brad's Girlfriend | Maddie, Brad's Girlfriend |
| LLee CunninghamLee, The Unhappy Wife | Lee, The Unhappy Wife |
| SStephen Lee DavisSteve, The Grocery Shopper | Steve, The Grocery Shopper |
 John FranchiDriver (uncredited) | Driver (uncredited) |
| AAnita StorrWedding Beach Goer (uncredited) | Wedding Beach Goer (uncredited) |
