A gang of robbers armed with a union army cannon rob the bank holding bounty Killer Acquasanta Joe's earnings to date. He pursues, crossing and double crossing along the way.
| Actor | Role |
|---|---|
 Ty HardinJeff Donovan | Jeff Donovan |
 Richard HarrisonCharlie Bennett | Charlie Bennett |
 Lincoln TateAquasante Joe / Holy Water Joe | Aquasante Joe / Holy Water Joe |
| SSiliva MonelliEstella | Estella |
 Giulio BaraghiniJim | Jim |
 Pietro CeccarelliSergeant Butch | Sergeant Butch |
 Tuccio MusumeciThe Sicilian | The Sicilian |
 Mario NovelliDonovan Henchman | Donovan Henchman |
 Fedele GentileThe General | The General |
 Alfredo RizzoOfficer | Officer |
| AAdriano VitaleNot listed | Not listed |
 Dante MaggioBanker | Banker |
 Sergio SerafiniConfederate Lieutenant | Confederate Lieutenant |
 Ugo BallesterPriest (uncredited) | Priest (uncredited) |