Hellboy and a rookie BPRD agent get stranded in 1950s rural Appalachia. There, they discover a small community haunted by witches, led by a local devil with a troubling connection to Hellboy's past: the Crooked Man.
| Actor | Role |
|---|---|
 Jack KesyHellboy | Hellboy |
 Jefferson WhiteTom Ferrell | Tom Ferrell |
 Adeline RudolphBobbie Jo Song | Bobbie Jo Song |
 Leah McNamaraEffie Kolb | Effie Kolb |
 Hannah MargetsonCora Fisher | Cora Fisher |
 Martin BassindaleThe Crooked Man | The Crooked Man |
 Joseph MarcellReverend Watts | Reverend Watts |
 Suzanne BertishGrammy Oakum | Grammy Oakum |
| BBodgan HaralambovYoung Tom | Young Tom |
 Carola ColomboSarah Huges | Sarah Huges |
| SSiyana NachevaAbby Riley | Abby Riley |
 Anton TrendafilovTom's Father | Tom's Father |
 Jonathan YungerDennis Gates | Dennis Gates |
 Michael FlemmingYoung Reverend Watts | Young Reverend Watts |
 Nathan CooperFarmhand | Farmhand |
 Laura GioshOld Woman | Old Woman |
| WWilliam KnoxKid | Kid |
| SSvetlana AtanasovaOld Effie | Old Effie |
| EElsie Chan BaYoung Bobbie Jo | Young Bobbie Jo |
| TTsveta DimovaBobbie Jo's Mother | Bobbie Jo's Mother |