Head Bush revolves around Jayaraj, his friends, foes, police officers, and the politicians who changed the course of the political scenario of Bengaluru in the 1970s. The film focuses on the rise and rise of Jayaraj - from a teenager to a rowdy to a mass hero.
| Actor | Role |
|---|---|
 DhananjayM. P. Jayaraj | M. P. Jayaraj |
 DevarajChief Minister Devraj Urs | Chief Minister Devraj Urs |
 YogeshGanga | Ganga |
 Vasishta N. SimhaKothwal Ramchandra | Kothwal Ramchandra |
 Sruthi HariharanRathnaprabha | Rathnaprabha |
 Raghu MukherjeeMDN | MDN |
 Payal RajputNot listed | Not listed |
| BBalu NagendraNot listed | Not listed |
 V. RavichandranNot listed | Not listed |
 Madhusudhan RaoNot listed | Not listed |