 Elijah WoodMumble (voice) | Mumble (voice) |
 Robin WilliamsRamon / Lovelace (voice) | Ramon / Lovelace (voice) |
 P!nkGloria (voice) | Gloria (voice) |
 E. G. DailyErik (voice) | Erik (voice) |
 Johnny A. SanchezLombardo (voice) | Lombardo (voice) |
 Lombardo BoyarRaul (voice) | Raul (voice) |
 Sofía VergaraCarmen (voice) | Carmen (voice) |
 CommonSeymour (voice) | Seymour (voice) |
 Hugo WeavingNoah (voice) | Noah (voice) |
 Brad PittWill (voice) | Will (voice) |
 Matt DamonBill (voice) | Bill (voice) |
 Carlos AlazraquiNestor (voice) | Nestor (voice) |
 Jeffrey GarciaRinaldo (voice) | Rinaldo (voice) |
 Ava AcresErik (voice) | Erik (voice) |
 Benjamin Flores Jr.Atticus (voice) | Atticus (voice) |
| MMeibh CampbellBo (voice) | Bo (voice) |
 Magda SzubanskiMiss Viola (voice) | Miss Viola (voice) |
 Hank AzariaMighty Sven (voice) | Mighty Sven (voice) |
 Richard CarterBryan (voice) | Bryan (voice) |
 Lee PerryWayne / Francesco / Eggbert / Leopard Seal (voice) | Wayne / Francesco / Eggbert / Leopard Seal (voice) |
| JJai SloperWeaner Pup (voice) | Weaner Pup (voice) |
| OOscar BeardWeaner Pup (voice) | Weaner Pup (voice) |
 Anthony LaPagliaAlpha Skua (voice) | Alpha Skua (voice) |
 Danny MannBrokebeak (voice) | Brokebeak (voice) |
| DDenise BlasorAdelie Chica (voice) | Adelie Chica (voice) |
 Roger NarayanIndian Penguin (voice) | Indian Penguin (voice) |
 Mason CottonAdditional Voices (voice) | Additional Voices (voice) |
 Joshua RushAdditional Voice (voice) | Additional Voice (voice) |
| LLillian Garrett-GroagAdditional Voices (voice) | Additional Voices (voice) |
 Veena BidashaAdditional Voices (voice) | Additional Voices (voice) |
