After enjoying a holiday romance, high school students Danny and Sandy are unexpectedly reunited when she transfers to Rydell High, where she must contend with cynical Rizzo and the Pink Ladies.
| Actor | Role |
|---|---|
 Julianne HoughSandy Young | Sandy Young |
 Aaron TveitDanny Zuko | Danny Zuko |
 Vanessa HudgensBetty Rizzo | Betty Rizzo |
 Keke PalmerMarty | Marty |
 Carly Rae JepsenFrenchy | Frenchy |
 Mario LópezVince Fontaine | Vince Fontaine |
 Carlos PenaVegaKenickie | Kenickie |
 Kether DonohueJan | Jan |
 Jordan FisherDoody | Doody |
 David Del RioPutzie | Putzie |
 Andrew CallSonny | Sonny |
 Wendell PierceCoach Calhoun | Coach Calhoun |
 Jessie JSinger | Singer |
 Joe JonasJohnny Casino | Johnny Casino |
 Jack LawlessThe Gamblers | The Gamblers |
 Cole WhittleThe Gamblers | The Gamblers |
 JinJoo LeeThe Gamblers | The Gamblers |
 Ana GasteyerPrincipal McGee | Principal McGee |
 Didi ConnVi | Vi |
 Barry PearlStan Weaver | Stan Weaver |
 Elle McLemorePatty Simcox | Patty Simcox |
 Noah RobbinsEugene | Eugene |
 Eve PlumbMrs. Murdock | Mrs. Murdock |
 Haneefah WoodBlanche | Blanche |
 Yvette Gonzalez-NacerCha-Cha | Cha-Cha |
 Jon Robert HallTom Chisum | Tom Chisum |
 Sam ClarkLeo | Leo |
 Jeremy HudsonErnie | Ernie |
 Nick BagaDancer | Dancer |
 Karen ChuangDancer | Dancer |