Gospel Hill tells the intersecting story of two men in the fictional South Carolina town of Julia. Danny Glover plays John Malcolm, the son of a slain civil rights activist. Jack Herrod (Tom Bower) is the former sheriff who never got to the bottom of the murder. Their paths begin to cross when a development corporation comes to town with plans to raze Julia's historic Gospel Hill.
| Actor | Role |
|---|---|
 Adam BaldwinCarl Herrod | Carl Herrod |
 Angela BassettSarah Malcolm | Sarah Malcolm |
 Tom BowerJack Herrod | Jack Herrod |
 Giancarlo EspositoDr. Palmer | Dr. Palmer |
 Danny GloverJohn Malcolm | John Malcolm |
 Taylor KitschJoel Herrod | Joel Herrod |
 Nia LongMrs. Palmer | Mrs. Palmer |
 RZALonnie | Lonnie |
 Julia StilesRosie | Rosie |
 Chris EllisL Donn Murray | L Donn Murray |
 Chlöe BaileyAnna | Anna |
 Samuel L. JacksonPaul Malcolm | Paul Malcolm |
 Phillip BlochGeorge | George |
| CC.K. BibbyDr. Bob Owens | Dr. Bob Owens |
| DDarlene BlackNurse | Nurse |
 Jason DownsTommy Duncan | Tommy Duncan |
| JJesse GoreCalvin | Calvin |
| RRalph GreeneLuther | Luther |
 David HainesInterviewer | Interviewer |
| FFelix JusticeCitizen | Citizen |
| JJason Duffy KlemmPolice Officer | Police Officer |
 Ted MansonErnest Hatch | Ernest Hatch |
| RRaquel OliverBlack Cop | Black Cop |
| LLee FreemanMiriam (President) | Miriam (President) |