As John Dannahay, a CIA agent stationed in Rome, plans the overthrow of an African government, he discovers one of his men has been in contact with agents from the other side. Before he can confront the traitor, the man seemingly goes crazy, sniping several people before taking an adulterous couple hostage in a hotel room.
| Actor | Role |
|---|---|
 Tony MusanteJohn Dannahay | John Dannahay |
 Claudia CardinaleAliki | Aliki |
 John ForsytheThe American Ambassador | The American Ambassador |
 John SteinerDonald Grayson | Donald Grayson |
 Renzo PalmerParenti | Parenti |
| AAngela GoodwinThe Ambassador's Wife | The Ambassador's Wife |
 Anna ZinnemannRenata | Renata |
 Fabrizio JovineInspector Moreno | Inspector Moreno |
 Wolfango SoldatiHarry Lambert | Harry Lambert |
 Gianrico TondinelliJack | Jack |
 Luciano CatenacciVincent | Vincent |
 Francesco CarneluttiAgostino | Agostino |
 Piero PalerminiBerto | Berto |
| RRuggero De DaninosDe Mauro | De Mauro |
 Giovanni Di BenedettoForeign Secretary | Foreign Secretary |
 Gioia ScolaMaria Soli | Maria Soli |
| MMauro BarabaniNot listed | Not listed |
| MMassimiliano BarattaNot listed | Not listed |
 Antonio MaimoneNot listed | Not listed |
| SSergio DoriaNot listed | Not listed |
| NNat BushNot listed | Not listed |
 John P. DulaneyNot listed | Not listed |
 Alessandro HaberBlondie | Blondie |