Nine filmmakers each profile a young girl from a different part of the world to weave a global tapestry of youth in the 21st century.
| Actor | Role |
|---|---|
 Liam NeesonNarrator (voice) | Narrator (voice) |
 Freida PintoNarrator (voice) | Narrator (voice) |
 Anne HathawayNarrator - Afghanistan (voice) | Narrator - Afghanistan (voice) |
 Alicia KeysNarrator - Cambodia (voice) | Narrator - Cambodia (voice) |
 Meryl StreepNarrator - Ethiopia (voice) | Narrator - Ethiopia (voice) |
 Cate BlanchettNarrator - Haiti (voice) | Narrator - Haiti (voice) |
 Priyanka Chopra JonasNarrator - India (voice) | Narrator - India (voice) |
 Kerry WashingtonNarrator - Nepal (voice) | Narrator - Nepal (voice) |
 Salma Hayek PinaultNarrator - Peru (voice) | Narrator - Peru (voice) |
 Selena GomezNarrator - Sierra Leone (voice) | Narrator - Sierra Leone (voice) |
 Sammy SheikOfficer Mansoor | Officer Mansoor |
 Said FarajSgt. Assif | Sgt. Assif |
 Chloë Grace MoretzYasmin (voice) | Yasmin (voice) |