 Ethan HawkeVincent Freeman | Vincent Freeman |
 Uma ThurmanIrene Cassini | Irene Cassini |
 Jude LawJerome Eugene Morrow | Jerome Eugene Morrow |
 Alan ArkinDetective Hugo | Detective Hugo |
 Loren DeanAdult Anton Freeman | Adult Anton Freeman |
 Gore VidalDirector Josef | Director Josef |
 Tony Shalhoub"German" | "German" |
 Ernest BorgnineCaesar | Caesar |
 Blair UnderwoodGeneticist | Geneticist |
 Xander BerkeleyDr. Lamar | Dr. Lamar |
 Jayne BrookMarie Freeman | Marie Freeman |
 Una DamonHead Nurse | Head Nurse |
 Elias KoteasAntonio Freeman | Antonio Freeman |
 Maya RudolphDelivery Nurse | Delivery Nurse |
 Elizabeth DennehyPreschool Teacher | Preschool Teacher |
 Mason GambleYounger Vincent | Younger Vincent |
| VVincent NielsonYounger Anton | Younger Anton |
 Chad ChristYoung Vincent | Young Vincent |
 William Lee ScottYoung Anton | Young Anton |
| CClarence GrahamPersonnel Officer | Personnel Officer |
| CCarlton BenbryGattaca Hoover | Gattaca Hoover |
 Susan Jennifer SullivanSequencing Customer | Sequencing Customer |
 Ken MarinoSequencing Technician | Sequencing Technician |
 Cynthia MartellsCavendish | Cavendish |
 Gabrielle ReeceGattaca Trainer | Gattaca Trainer |
| RRyan DorinTwelve-Fingered Pianist | Twelve-Fingered Pianist |
 Dean NorrisCop on the Beat | Cop on the Beat |
 Russell MiltonGattaca Detective | Gattaca Detective |
| GGeorge Marshall RugeBeaten Detective | Beaten Detective |
| SSteve BessenBlood Test Detective | Blood Test Detective |
