Garfield escapes from the car on a trip to the vet and finds the place where he grew up.
| Actor | Role |
|---|---|
| LLorenzo MusicGarfield (voice) | Garfield (voice) |
| TThom HugeJon Arbuckle / Chef (voice) | Jon Arbuckle / Chef (voice) |
 Gregg BergerOdie / Ali Cat / Gang Cat #1 / Sly (voice) | Odie / Ali Cat / Gang Cat #1 / Sly (voice) |
 George WendtRaoul / Member of the Claws (voice) | Raoul / Member of the Claws (voice) |
| SSandi HugeMom (voice) | Mom (voice) |
 Julie PayneDoc (voice) | Doc (voice) |
 C. Lindsay WorkmanGrandfather (voice) | Grandfather (voice) |
 Allyce BeasleyGirl Cat 2 / Girl Cat 3 (voice) | Girl Cat 2 / Girl Cat 3 (voice) |
 Desiree GoyetteGirl Cat 1 (voice) | Girl Cat 1 (voice) |