Garfield plays multiple roles including ancient Egyptian royalty, a fairyland kitten, a movie "stunt cat" and more!
| Actor | Role |
|---|---|
| LLorenzo MusicGarfield (voice) | Garfield (voice) |
| TThom HugeJon Arbuckle/ Caveman #1 / Junior / Soldier / Computer (voice) | Jon Arbuckle/ Caveman #1 / Junior / Soldier / Computer (voice) |
 Gregg BergerOdie / Jester / Scientist #1 / Cave Cat Narrator (voice) | Odie / Jester / Scientist #1 / Cave Cat Narrator (voice) |
 Desiree GoyetteChloe / Sara (voice) | Chloe / Sara (voice) |
| NNino TempoLuigi / Black Bart (voice) | Luigi / Black Bart (voice) |
 Hal SmithGeorge Frideric Handel / Larry (voice) | George Frideric Handel / Larry (voice) |
| HHeather KerrLittle Sara (voice) | Little Sara (voice) |
| SSandi HugeGarfield's Mother / Sara's Mother (voice) | Garfield's Mother / Sara's Mother (voice) |
| CCarolyn DavisOlder Sara (voice) | Older Sara (voice) |
 Frank WelkerCommander Mendelson (voice) | Commander Mendelson (voice) |
 C. Lindsay WorkmanGod (voice) | God (voice) |
| EEd BogasAdditional Voices (voice) | Additional Voices (voice) |