This film is a chronicle of painter Frida Kahlo, and her encounter with the personalities of her time. Despite being confied to a wheelchair as a result of polio, operations and amputations, she faces and traces some of the most colorful and controversial aspects of Mexican history, during the dominant time of Mexican muralism.
| Actor | Role |
|---|---|
 Ofelia MedinaFrida Kahlo | Frida Kahlo |
 Juan José GurrolaDiego Rivera | Diego Rivera |
 Max KerlowLeon Trotsky | Leon Trotsky |
 Claudio BrookGuillermo Kahlo | Guillermo Kahlo |
 Salvador SánchezDavid Alfaro Siqueiros | David Alfaro Siqueiros |
 Cecilia ToussaintFrida's Sister | Frida's Sister |
| ZZiwta KerlowTrotsky's Wife | Trotsky's Wife |
| VValentina Leduc NavarroYoung Frida | Young Frida |
 Lolita CortésSister of Young Frida | Sister of Young Frida |
 Gina MorettNurse | Nurse |
| JJuan Ángel MartínezWoodworker | Woodworker |
 Odiseo BichirYoung sandinista | Young sandinista |
 Bruno BichirYoung Sandinista | Young Sandinista |