 Clint EastwoodManco | Manco |
 Lee Van CleefCol. Douglas Mortimer | Col. Douglas Mortimer |
 Gian Maria VolontéEl Indio | El Indio |
| MMara KruppMary | Mary |
 Luigi PistilliGroggy, Member of Indio's Gang | Groggy, Member of Indio's Gang |
 Klaus KinskiJuan Wild - The Hunchback | Juan Wild - The Hunchback |
 Luis RodríguezManuel, Member of Indio's Gang | Manuel, Member of Indio's Gang |
 Benito StefanelliLuke 'Hughie' | Luke 'Hughie' |
| PPanos PapadopulosSancho Perez, Member of Indio's Gang | Sancho Perez, Member of Indio's Gang |
 Aldo SambrellCuchillo | Cuchillo |
 Roberto CamardielTucumcari Station Clerk | Tucumcari Station Clerk |
 Joseph EggerOld Prophet | Old Prophet |
 Tomás BlancoTucumcari Sheriff | Tucumcari Sheriff |
 Lorenzo RobledoTomaso, Indio's Traitor | Tomaso, Indio's Traitor |
 Dante MaggioCarpenter in Cell with El Indio | Carpenter in Cell with El Indio |
 Sergio MendizábalTucumcari Bank Manager | Tucumcari Bank Manager |
| DDiana RabitoCallaway's Beautiful Girl in Tub | Callaway's Beautiful Girl in Tub |
| GGiovanni TaralloSanta Cruz Telegraphist | Santa Cruz Telegraphist |
 Mario MeniconiTrain Conductor | Train Conductor |
 Mario BregaNiño, Member of Indio's Gang | Niño, Member of Indio's Gang |
 José TerrónGuy Calloway, Mortimer's 1st Criminal (uncredited) | Guy Calloway, Mortimer's 1st Criminal (uncredited) |
 José Marco'Baby' Red Cavanaugh (uncredited) | 'Baby' Red Cavanaugh (uncredited) |
| WWerner AbrolatSlim, Member of Indio's Gang (uncredited) | Slim, Member of Indio's Gang (uncredited) |
 Frank BrañaBlackie, Member of Indio's Gang (uncredited) | Blackie, Member of Indio's Gang (uncredited) |
 José CanalejasChico, Member of Indio's Gang (uncredited) | Chico, Member of Indio's Gang (uncredited) |
 Antonio Molino RojoFrisco, Member of Indio's Gang (uncredited) | Frisco, Member of Indio's Gang (uncredited) |
 Jesús GuzmánCarpetbagger on Train (uncredited) | Carpetbagger on Train (uncredited) |
 Ricardo PalaciosTucumcari Saloon Keeper (uncredited) | Tucumcari Saloon Keeper (uncredited) |
 Guillermo MéndezWhite Rocks Sheriff (uncredited) | White Rocks Sheriff (uncredited) |
 Rosemary DexterMortimer's Sister (uncredited) | Mortimer's Sister (uncredited) |
