Mike Kildare, a swaggering youth from New York City's Bowery at the turn of the century, comes to the defense of Mamie Rose, a mender in a secondhand clothing shop, when his own gang of Irish-Americans insult her.
| Actor | Role |
|---|---|
 Mary PhilbinMamie Rose | Mamie Rose |
 Pat O'MalleyMike Kildare | Mike Kildare |
 William Collier Jr.Max Davidson | Max Davidson |
 Lincoln PlumerMike Flavin (the boss) | Mike Flavin (the boss) |
 Ed BradyJackie Doodle (as Edwin J. Brady) | Jackie Doodle (as Edwin J. Brady) |
 Max DavidsonOld Levi | Old Levi |
 Kate PriceMrs. Flannigan | Mrs. Flannigan |
 Charles MurrayMamie's Father | Mamie's Father |
 James SheridanOle Larsen (as Sherry Tansey) | Ole Larsen (as Sherry Tansey) |
 Steve MurphyChuck Connors | Chuck Connors |
 Tom O'BrienPhiladelphia O'Brien | Philadelphia O'Brien |