Amanda, after testing positive for the BRCA gene mutation, has a specific plan to say goodbye to her breasts the weekend before her preventative double mastectomy, but her sister comes to town with a list of her own ideas for the weekend.
| Actor | Role |
|---|---|
 Alicia WittAmanda | Amanda |
 Rebekah WardJaime | Jaime |
 Christopher MeisterNot listed | Not listed |
| RRichard BenedykHotel Bar Eavesdropper | Hotel Bar Eavesdropper |
 Kim DeJesusBeautiful Woman | Beautiful Woman |
 Peggy RoederSupport Group Host | Support Group Host |
 Janet Ulrich BrooksSupport Group Member | Support Group Member |
| RRobyn OkrantSupport Group Member | Support Group Member |
 Luke PerryRalph | Ralph |
 Sarafina VecchioNurse | Nurse |